Investments in Independent Companies

• Surgi-Vision has developed “real-time” Visual Functional MRI Technology. The Company is targeting clinical solutions in two areas: MR-Guided Deep Brain Stimulation (DBS) and Cardiac Ablation to treat Atrial Fibrillation.
• Cardiovascular Solutions, Inc. has identified unmet needs in the diagnostics of several types of CVD that can be addressed with their core technology.
• Medivation, Inc. has several small-molecule drugs in development with a product pipeline aimed at treating three large, unmet medical needs: Alzheimer's disease, Huntington's disease and hormone-refractory prostate cancer.
• SpineMedica, Inc. is a development stage company focused on medical device technologies for application in the spine. In August, 2007, SpineMedica was acquired by MiMedx, Inc. (www.MiMedx.com) MiMedx is an early-stage development company with a focus in orthopedics solutions through the development and application of biomaterials.